Article
Systematic Engineering of Intra-Articular Drug Release Profiles Reveals a Key Determinant of Disease-Modifying Efficacy in Post-Traumatic Osteoarthritis
2026-06-03
Abstract excerpt
Post-traumatic osteoarthritis (PTOA) is a progressive joint disease for which no disease-modifying osteoarthritis drugs (DMOADs) have been approved. Although injectable drug delivery systems can prolong therapeutic retention within the joint, it remains unclear whether local drug release kinetics influence disease-modifying efficacy. Here, we developed a modular platform of injectable supramolecular hydrogels usin...
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Identifiers and source
- Literature Corpus work
- 5e39e24d-f9eb-5dba-9a90-6c4e22ef93d5
- DOI
- 10.64898/2026.05.30.728894