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At the Crossroads of Fate—Somatic Cell Lineage Specification in the Fetal Gonad

15 May 2018

Abstract excerpt

The reproductive endocrine systems are vastly different between males and females. This sexual dimorphism of the endocrine milieu originates from sex-specific differentiation of the somatic cells in the gonads during fetal life. Most gonadal somatic cells arise from the adrenogonadal primordium. After separation of the adrenal and gonadal primordia, the gonadal somatic cells initiate sex-specific differentiation...

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PMID: 29771299
DOI: 10.1210/er.2018-00010

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