Article

AF2-multimer guided high accuracy prediction of typical and atypical ATG8 binding motifs

2022-09-26

Abstract excerpt

Macroautophagy/autophagy is an intracellular degradation process central to cellular homeostasis and defense against pathogens in eukaryotic cells. Regulation of autophagy relies on hierarchical binding of autophagy cargo receptors and adaptors to ATG8/LC3 protein family members. Interactions with ATG8/LC3 are typically facilitated by a conserved, short linear sequence, referred to as the ATG8/LC3 interacting moti...

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Identifiers and source

Literature Corpus work: 3766da58-be34-5810-b623-40386035eb97
DOI: 10.1101/2022.09.25.509395

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