AlphaFold-multimer predicts ATG8 protein binding motifs crucial for autophagy research

Abstract excerpt

In this issue of PLOS Biology, Ibrahim and colleagues demonstrate how AlphaFold-multimer, an artificial intelligence-based structure prediction tool, can be used to identify sequence motifs binding to the ATG8 family of proteins central to autophagy.Proteins are structural and executing macromolecules essential for life in all biological systems.Insight into proteins structures is required for detailed...

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