Article

Discovery and Validation of Alternatives to VSV-G for Pseudotyping of Lentiviral Vectors for In Vivo Delivery of Anti-Tumor Transgenes

2025-03-07

Abstract excerpt

<h4>ABSTRACT</h4> Though cell therapy for cancer is now widely used commercially and has been efficacious for tens of thousands of patients, conventional manufacturing methods are expensive and difficult to scale. An alternative approach is to deliver the relevant anti-tumor transgenes to T cells in vivo in the patient. Such “ in vivo cell therapy” methods promise to be more scalable, with reduced cost of goods...

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Literature Corpus work: 37409fd6-28f2-55a3-82bc-dabdf6c984ea
DOI: 10.1101/2025.03.03.641199

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