Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transduction of γδ T cells with Baboon envelope pseudotyped lentiviral vector encoding chimeric antigen receptors for translational and clinical applications

6 Jun 2025

Abstract excerpt

γδ T cells represent a promising cell platform for adoptive cell therapy. Their natural anti-tumor reactivity and HLA-independent target cell recognition make them an attractive platform for allogeneic adoptive immunotherapy clinical interventions. Initial clinical trials exploring allogeneic γδ T-cell therapies have demonstrated encouraging safety profiles. However, their therapeutic efficacy, especially against...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CAR-T cell therapy research
Share to Viral Infectious Diseases and Gene Expression in Insects
Share to Virus-based gene therapy research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40547029
DOI: 10.3389/fimmu.2025.1548630

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transduction of γδ T cells with Baboon envelope pseudotyped lentiviral vector encoding chimeric antigen receptors for translational and clinical applicationsPMID 40547029Read ↗

The potential of γδ CAR and TRuC T cells: An unearthed treasureSemantic proximity Read ↗

Efficient and Robust NK-Cell Transduction With Baboon Envelope Pseudotyped LentivectorSemantic proximity Read ↗

Multipurposing CARs: Same engine, different vehiclesSemantic proximity Read ↗

Progress in Pseudotyping Lentiviral Vectors Towards Cell-Specific Gene Delivery In VivoSemantic proximity Read ↗

Vectofusin-1 Improves Transduction of Primary Human Cells with Diverse Retroviral and Lentiviral Pseudotypes, Enabling Robust, Automated Closed-System ManufacturingSemantic proximity Read ↗

Efficient multiplex non-viral engineering and expansion of polyclonal γδ CAR-T cells for immunotherapySemantic proximity Read ↗

Bispecific T-cells Expressing Polyclonal Repertoire of Endogenous γδ T-cell Receptors and Introduced CD19-specific Chimeric Antigen ReceptorSemantic proximity Read ↗

Engineering and Design of Chimeric Antigen ReceptorsSemantic proximity Read ↗

Baboon envelope LVs efficiently transduced human adult, fetal, and progenitor T cells and corrected SCID-X1 T-cell deficiencySemantic proximity Read ↗

The Past, Present, and Future of Non-Viral CAR T CellsSemantic proximity Read ↗

Recent Advances in Allogeneic CAR-T CellsSemantic proximity Read ↗

Prospects for chimeric antigen receptor (CAR) γδ T cells: A potential game changer for adoptive T cell cancer immunotherapy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.