Article

Post-translational polymodification of <i>β</i> 1 tubulin regulates motor protein localisation in platelet production and function

2019-04-01

Abstract excerpt

In specialised cells, the expression of specific tubulin isoforms and their subsequent post-translational modifications drive and coordinate unique morphologies and behaviours. The mechanisms by which β 1 tubulin, the platelet and megakaryocyte (MK) lineage restricted tubulin isoform, drives platelet production and function remains poorly understood. We investigated the roles of two key post-translational polymod...

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Literature Corpus work: 373192c3-13cc-5bbd-ad27-9af22f4fef77
DOI: 10.1101/595868

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