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Article

An essential role for α4A-tubulin in platelet biogenesis

1 Feb 2019

Abstract excerpt

During platelet biogenesis, microtubules (MTs) are arranged into submembranous structures (the marginal band) that encircle the cell in a single plane. This unique MT array has no equivalent in any other mammalian cell, and the mechanisms responsible for this particular mode of assembly are not fully understood. One possibility is that platelet MTs are composed of a particular set of tubulin isotypes that carry...

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PMID: 30760556
DOI: 10.26508/lsa.201900309

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