Article

Mct11 deficiency alters hepatic glucose metabolism and energy homeostasis

2021-09-08

Abstract excerpt

<h4>SUMMARY</h4> Genetic variation at the SLC16A11 locus contributes to the disproportionate impact of type 2 diabetes (T2D) on Latino populations. We recently demonstrated that T2D risk variants reduce SLC16A11 liver expression and function of MCT11, the monocarboxylate transporter encoded by the SLC16A11 gene. Here, we show that SLC16A11 expression within the liver is primarily localized to the low oxygen p...

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Literature Corpus work: 3708600d-8dc6-5def-b45c-d366988013d1
DOI: 10.1101/2021.09.08.459307

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