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The SLC16A11 risk haplotype is associated with decreased insulin action, higher transaminases and large-size adipocytes

21 Nov 2018

Abstract excerpt

Objective A haplotype at chromosome 17p13 that reduces expression and function of the solute carrier transporter SLC16A11 is associated with increased risk for type 2 diabetes in Mexicans. We aim to investigate the detailed metabolic profile of SLC16A11 risk haplotype carriers to identify potential physiological mechanisms explaining the increased type 2 diabetes risk. Design Cross-sectional study. Methods We...

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PMID: 30475225
DOI: 10.1530/eje-18-0677

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