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Article

Bladder cancer organoids as a functional system to model different disease stages and therapy response

18 Apr 2023

Abstract excerpt

Bladder Cancer (BLCa) inter-patient heterogeneity is the primary cause of treatment failure, suggesting that patients could benefit from a more personalized treatment approach. Patient-derived organoids (PDOs) have been successfully used as a functional model for predicting drug response in different cancers. In our study, we establish PDO cultures from different BLCa stages and grades. PDOs preserve the...

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PMID: 37072390
DOI: 10.1038/s41467-023-37696-2

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