Article
A case of BRAF-mutant High-Grade Glioma with Pleomorphic and Pseudopapillary Features (HPAP) mimicking PLNTY but Exhibiting Aggressive Clinical Behavior
2025-08-27
Abstract excerpt
<title>Abstract</title> <p>Background High-grade glioma with pleomorphic and pseudopapillary features (HPAP) is a recently recognized glioma subtype defined by DNA methylation profiling. While it exhibits overlapping histological features with various CNS tumors, such as polymorphous low-grade neuroepithelial tumor of the young (PLNTY) and pleomorphic xanthoastrocytoma, its molecular pathogenesis and clinical beh...
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Identifiers and source
- Literature Corpus work
- 36b87239-59da-5f86-8472-d01a6bc01295
- DOI
- 10.21203/rs.3.rs-7429677/v1
