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Genome-Wide Discovery of Genes Required for Capsule Production by Uropathogenic Escherichia coli

25 Oct 2017

Abstract excerpt

ABSTRACT Uropathogenic Escherichia coli (UPEC) is a major cause of urinary tract and bloodstream infections and possesses an array of virulence factors for colonization, survival, and persistence. One such factor is the polysaccharide K capsule. Among the different K capsule types, the K1 serotype is strongly associated with UPEC infection. In this study, we completely sequenced the K1 UPEC urosepsis strain PA45B...

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PMID: 29066548
DOI: 10.1128/mbio.01558-17

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