Article

Microscaled Proteogenomic Methods for Precision Oncology

2019-10-08

Abstract excerpt

Cancer proteogenomics integrates genomics, transcriptomics and mass spectrometry (MS)-based proteomics to gain insights into cancer biology and treatment efficacy. A proteogenomics approach was therefore developed for frozen core biopsies using tissue-sparing specimen processing with a “microscaled” proteomics workflow. For technical proof-of-principle, biopsies from ERBB2 positive breast cancers before and 48-72...

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Literature Corpus work: 36427634-b0ac-50a6-a14b-6e75d8e51a53
DOI: 10.1101/796318

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