Article

Gastrointestinal involvement attenuates COVID-19 severity and mortality

2020-09-09

Abstract excerpt

Given that gastrointestinal (GI) symptoms are a prominent extrapulmonary manifestation of coronavirus disease 2019 (COVID-19), we investigated the impact of GI infection on disease pathogenesis in three large cohorts of patients in the United States and Europe. Unexpectedly, we observed that GI involvement was associated with a significant reduction in disease severity and mortality, with an accompanying reduction...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 36222c53-dd66-5873-90c4-b0e8c5c255d5
DOI: 10.1101/2020.09.07.20187666

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Gastrointestinal involvement attenuates COVID-19 severity and mortalityDOI 10.1101/2020.09.07.20187666Read

Gastrointestinal Symptoms are Quantitatively and Biologically Associated with COVID-19 SeveritySemantic proximity Read

Reduced SARS-CoV-2 infection and altered antiviral transcriptional response in IBD intestinal organoidsSemantic proximity Read

Alimentary System is Directly Attacked by SARS-COV-2 and Further Prevents Immune Dysregulation Caused by COVID-19Semantic proximity Read

Reduced SARS-CoV-2 infection levels and pathotype specific altered antiviral transcriptional response in IBD intestinal organoidsSemantic proximity Read

Gut microbiota diversity and C-Reactive Protein are predictors of disease severity in COVID-19 patientsSemantic proximity Read

Relative Abundance of SARS-CoV-2 Entry Genes in the Enterocytes of the Lower Gastrointestinal TractSemantic proximity Read

Intestinal inflammation modulates the expression of ACE2 and TMPRSS2 and potentially overlaps with the pathogenesis of SARS-CoV-2 related diseaseSemantic proximity Read

Single‐cell analyses reveal SARS‐CoV‐2 interference with intrinsic immune response in the human gutSemantic proximity Read

Relative Abundance of SARS-CoV-2 Entry Genes in the Enterocytes of the Lower Gastrointestinal TractSemantic proximity Read

Risks of digestive diseases in long COVID: Evidence from a large-scale cohort studySemantic proximity Read

Identification of SARS-CoV-2 Persistent Intestinal Epithelial Syndrome (SPIES) as a Novel Disease Entity using Clinical, Histologic, and RNA Programmatic DataSemantic proximity Read

Cirrhosis-associated immune dysfunction reflects impaired intestinal CD8αβ⁺ intraepithelial lymphocyte compartmentalizationSemantic proximity Read