Mapping Enzyme Activity in Living Systems by Real-Time Mid-Infrared Photothermal Imaging of Nitrile Chameleons

Abstract excerpt

<title>Abstract</title> <p>Enzymes are vital components in a variety of physiological and biochemical processes. Participation of various enzyme species are required for many biological events and signaling networks. Thus, spatially mapping the activity of multiple enzymes in a living system is significant for elucidating enzymatic functions in health and connections to diseases. Here, we report the development o...

Topics

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• Catalytic Domain
• Cell Adhesion Molecules Research
• Class I Phosphatidylinositol 3-Kinases
• Colorimetry
• Mutation
• Nanoplatforms for cancer theranostics
• Peptidase Inhibition and Analysis
• Protease and Inhibitor Mechanisms

Identifiers and source

Literature Corpus work

36077ca0-a3d3-5abf-8028-9668f58cd0d6

DOI

10.21203/rs.3.rs-2592139/v1