Article
Enzyme-Free Colorimetric Method for Fast Detection of PIK3CA Gene Mutation by Praseodymia Nanorods.
Analytical chemistry - 7 Feb 2023
Jiang Lei, Wang Meng, Li Youxun, Zhang Shuyuan, Zhu Xiudong, Zhong Junjie, Sun Jingtao, Tinoco Miguel, Chen Xiaowei
Abstract excerpt
The frequently mutated phosphatidylinositol 3-kinase catalytic subunit alpha (PIK3CA) gene is associated with multiple tumors and endocytosis of viruses. Identification of muted nucleotides at the hotspot can help in finding the susceptible people who are vulnerable to cancers and viruses. Herein, a simple enzyme-free colorimetric method is developed for the quick detection of PIK3CA gene mutations. The main...
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