Article

Viral Complexity: Amino acid co-evolution in viral genomes as a possible metric

2017-11-13

Abstract excerpt

<h4>ABSTRACT</h4> Viruses are simultaneously simple and complex. Simple because they have barely around ten types of proteins compared to tens of thousands of proteins in bacteria. Complex because amino acid mutation rates are very high, challenging host immune system and drugs. In this work we use the co-evolution of amino acids and the network characteristics that arise out of it to describe the complexity hidd...

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Literature Corpus work: 35f2a1e8-c4d2-555a-8ffd-376ee75d75eb
DOI: 10.1101/159541

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