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Cell Culture Adaptation of H3N2 Influenza Virus Impacts Acid Stability and Reduces Ferret Airborne Transmission

2021-03-11

Abstract excerpt

Airborne transmission of seasonal and pandemic influenza viruses is responsible for their epidemiological success and public health burden in humans. Efficient airborne transmission of H1N1 influenza virus relies on receptor specificity and pH of fusion of the surface glycoprotein hemagglutinin (HA). In this study, we examine the role of HA pH of fusion on transmissibility of a cell culture-adapted H3N2 virus. Mut...

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Literature Corpus work
35e33244-2b30-5a2a-a437-2ad7de053d3d
DOI
10.20944/preprints202103.0297.v1
Open publication

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Cell Culture Adaptation of H3N2 Influenza Virus Impacts Acid Stability and Reduces Ferret Airborne TransmissionDOI 10.20944/preprints202103.0297.v1
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