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Article

EZH2 as a Potential Target for NAFLD Therapy

16 Nov 2020

Abstract excerpt

Non-alcoholic fatty liver disease (NAFLD) is a complex disease that is affected by genetic predisposition and epigenetic modification. Deregulation of epigenetic pathways is now recognized as a frequent event in NAFLD, and understanding the mechanistic roles of these epigenetic factors may lead to new strategies for NAFLD treatment. Enhancer of zeste homolog 2 (EZH2) catalyzes methylation on Lys 27 of histone H3,...

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PMID: 33207561
DOI: 10.3390/ijms21228617

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