Article
Polymorphic estrogen receptor binding site causes CD2-dependent sex bias in the susceptibility to autoimmune diseases
2021-04-02
Abstract excerpt
<title>Abstract</title> <p>Complex autoimmune diseases are sexually dimorphic. An interplay between predisposing genetics and sex-related factors likely determines the sex discrepancy in the immune response, but conclusive evidence is lacking regarding the underlying molecular mechanisms. Using forward genetics, we positionally identified a polymorphic estrogen receptor binding site that regulates <italic>CD2</it...
Topics
Open a Topic to create a Post that cites this publication.
Identifiers and source
- Literature Corpus work
- 356e13ae-eb8a-5bf4-9d60-d9a0a3552ef4
- DOI
- 10.21203/rs.3.rs-337166/v1