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ABCC10-mediated Oxaliplatin resistance in colorectal cancer cells was alleviated by intense endoplasmic reticulum stress (ERS) / IRE1α

2022-08-24

Abstract excerpt

<h4>Background: </h4> Oxaliplatin resistance is a challenge in treating colorectal cancer (CRC) patients, contributory to the failure in chemotherapy and the risks in relapse and metastasis. However, the mechanism of Oxaliplatin resistance has not been completely elucidated. Methods Microarray screening, western blot and qPCR on clinic CRC samples were conducted to select the target gene ABCC10 transporter. The C...

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Literature Corpus work
35535c2b-2b39-56a7-b594-f53614e61a97
DOI
10.21203/rs.3.rs-1947659/v1
Open publication

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ABCC10-mediated Oxaliplatin resistance in colorectal cancer cells was alleviated by intense endoplasmic reticulum stress (ERS) / IRE1αDOI 10.21203/rs.3.rs-1947659/v1
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