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Article

Use of RetroNectin in studies requiring in vitro HIV-1 infection of human hematopoietic stem/progenitor cells

2017-05-25

Abstract excerpt

Human immunodeficiency virus (HIV) causes damage, directly or indirectly, to the whole hematopoietic system including CD34 + hematopoietic stem/progenitor cells (HSPC). CXCR4-tropic strains of HIV-1 may be potent to affect the function of CD34 + CXCR4 + progenitor cells either by infecting the cells or by modifying the dynamics of more differentiated hematopoietic cells. However, CD34 + cells are known for the...

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Literature Corpus work
3548be9f-671c-5cbc-b25c-dd6d3da6bcf6
DOI
10.1101/142075
Open publication

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