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Article

Optimization of Fibronectin-Assisted Retroviral Gene Transfer into Human CD34 <sup>+</sup> Hematopoietic Cells

10 Dec 1997

Abstract excerpt

Efficient retroviral gene transfer into hematopoietic stem and progenitor cells can be achieved by co-localizing retrovirus and target cells on specific adhesion domains of recombinant fibronectin (FN) fragments. In this paper, we further optimize this technology for human CD34+ cells. Investigating the role of cytokine prestimulation in retrovirus-mediated gene transfer on plates coated with the recombinant FN...

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PMID: 9449373
DOI: 10.1089/hum.1997.8.18-2193

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Optimization of Fibronectin-Assisted Retroviral Gene Transfer into Human CD34 <sup>+</sup> Hematopoietic CellsPMID 9449373Read ↗

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