Article

Neural crest cell derived DKK1 modulates Wnt signalling in the second heart field to orchestrate cardiac outflow tract development

2025-04-01

Abstract excerpt

Heart morphogenesis is highly complex, and depends on the generation of diverse cell types which interact with each other in an orchestrated manner to remodel the primitive heart tube into a functional organ. Cardiac outflow tract formation critically depends on continued contribution of cardiac progenitor cells from the anterior second heart field to ensure proper growth of the outflow tract. Prior to entering th...

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Literature Corpus work: 3534bd90-53b9-5dbc-ac24-6037be19e35b
DOI: 10.1101/2025.03.27.645622

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