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Transcriptomic mapping of key reproductive and metabolic tissues and oocytes in mouse models of polycystic ovary syndrome

2022-08-11

Abstract excerpt

Excessive androgen production and obesity are key to Polycystic ovary syndrome (PCOS) pathogenesis. PCOS-like mouse models induced by androgen exposure include the prenatal androgenized (PNA), peripubertal androgenized, and overexpression of nerve growth factor in theca cells (17NF), as well as the effect of diet-induced maternal obesity model on offspring. To reveal the molecular features of these models, we perf...

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Literature Corpus work
352fa61f-5264-5f94-b371-cf2e59e7a17c
DOI
10.21203/rs.3.rs-1917590/v1
Open publication

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Transcriptomic mapping of key reproductive and metabolic tissues and oocytes in mouse models of polycystic ovary syndromeDOI 10.21203/rs.3.rs-1917590/v1
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