Article

The development of trait anxiety in nonhuman primates during the first year of life

2025-05-29

Abstract excerpt

Anxious Temperament (AT) is a nonhuman primate phenotype that models childhood behavioral inhibition, a prominent risk factor for anxiety disorders and stress-related psychopathology. To understand its earliest antecedents, we characterized AT’s developmental trajectory over the first year of life. Infant monkeys (n=35, 24 female) were longitudinally phenotyped for AT by assessing threat-related increases in freez...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 351db8e0-93b5-5f4f-902a-bbebf7577167
DOI: 10.1101/2025.05.29.654506

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The development of trait anxiety in nonhuman primates during the first year of lifeDOI 10.1101/2025.05.29.654506Read

The Development of Trait Anxiety in Nonhuman Primates During the First Year of Life.Semantic proximity Read

Heightened extended amygdala metabolism following threat characterizes the early phenotypic risk to develop anxiety-related psychopathology.Semantic proximity Read

Infant Inhibited Temperament in Primates Predicts Adult Behavior, is Heritable, and is Associated with Anxiety-Relevant Genetic VariationSemantic proximity Read

Infant inhibited temperament in primates predicts adult behavior, is heritable, and is associated with anxiety-relevant genetic variation.Semantic proximity Read

Research review: a neuroscience framework for pediatric anxiety disorders.Semantic proximity Read

A translational neuroscience approach to understanding the development of social anxiety disorder and its pathophysiology.Semantic proximity Read

Differentially methylated plasticity genes in the amygdala of young primates are linked to anxious temperament, an at risk phenotype for anxiety and depressive disorders.Semantic proximity Read

Amygdalar and hippocampal substrates of anxious temperament differ in their heritability.Semantic proximity Read

Mechanisms underlying the early risk to develop anxiety and depression: A translational approach.Semantic proximity Read

Neural mechanisms underlying heterogeneity in the presentation of anxious temperament.Semantic proximity Read

Genetic influences on behavioral inhibition and anxiety in juvenile rhesus macaques.Semantic proximity Read

Early-life stress, corpus callosum development, hippocampal volumetrics, and anxious behavior in male nonhuman primates.Semantic proximity Read