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Article

Amygdalar and hippocampal substrates of anxious temperament differ in their heritability.

Nature - 12 Aug 2010

Oler Jonathan A, Fox Andrew S, Shelton Steven E, Rogers Jeffrey, Dyer Thomas D, Davidson Richard J, Shelledy Wendy, Oakes Terrence R, Blangero John, Kalin Ned H

Abstract excerpt

Anxious temperament (AT) in human and non-human primates is a trait-like phenotype evident early in life that is characterized by increased behavioural and physiological reactivity to mildly threatening stimuli. Studies in children demonstrate that AT is an important risk factor for the later development of anxiety disorders, depression and comorbid substance abuse. Despite its importance as an early predictor of...

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Identifiers

PMID: 20703306
DOI: 10.1038/nature09282
PMCID: PMC2998538

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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