Article
Genetically modified Lactococcus lactis: novel tools for drug delivery
2006-05-01
Abstract excerpt
The dairy bacterium Lactococcus lactis can be genetically engineered to secrete bioactive cytokines. This enabled the development of an entirely novel drug delivery system: topical and active delivery of therapeutic proteins by genetically modified micro-organisms. In mice, intestinal inflammation can be successfully treated with interleukin-10- (IL-10) or trefoil factor-secreting L. lactis. In human application,...
Topics
Open a Topic to create a Post that cites this publication.
- Bacteriophages and microbial interactions
- Cancer Research and Treatments
- Clostridium difficile and Clostridium perfringens research
- Escherichia coli research studies
- Infant Nutrition and Health
- Probiotics and Fermented Foods
- Transgenic Plants and Applications
- Viral gastroenteritis research and epidemiology
Identifiers and source
- Literature Corpus work
- 34f7986c-9b4f-5ba3-b293-263562f05dca
- DOI
- 10.1111/j.1471-0307.2006.00255.x