Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Synthesis and structure of a new thiazoline-based palladium(II) complex that promotes cytotoxicity and apoptosis of human promyelocytic leukemia HL-60 cells

7 Oct 2020

Abstract excerpt

Abstract Cisplatin is one of the most widely used chemotherapeutic agents in the treatment of different tumors but has high toxicity and side effects. Therefore, the synthesis of new chemotherapeutic agents is necessary, so that they are effective in the treatment of cancer while avoiding such toxicity. In this study, we have synthesized and characterized a palladium(II) complex, [PdCl2(µ-PyTT)2]Cl2·4H2O...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Metal complexes synthesis and properties
Share to Synthesis and biological activity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33028870
DOI: 10.1038/s41598-020-73488-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Synthesis and structure of a new thiazoline-based palladium(II) complex that promotes cytotoxicity and apoptosis of human promyelocytic leukemia HL-60 cellsPMID 33028870Read ↗

ROS-mediated antitumor activity, apoptosis, and molecular docking studies of platinum (II) coordination complexes bearing 2-(diphenylphosphino)pyridine ligandSemantic proximity Read ↗

Fresh Platinum Complexes with Promising Antitumor ActivitySemantic proximity Read ↗

Metal-based anticancer drugs: From a past anchored in platinum chemistry to a post-genomic future of diverse chemistry and biologySemantic proximity Read ↗

Ruthenium(II) Complexes with 2-Phenylimidazo[4,5-f][1,10]phenanthroline Derivatives that Strongly Combat Cisplatin-Resistant Tumor CellsSemantic proximity Read ↗

Apoptotic and anti-proliferative activity of novel platinum complex [Pt((E)-N-((E)-4-hydroxy-3-methoxybenzylidene)-2- (pyridine-2-ylmethylene)hydrazine-1-carbothioamide)] against Ehrlich Ascites carcinoma (EAC) cells in vivoSemantic proximity Read ↗

Platinum-containing compound platinum pyrithione is stronger and safer than cisplatin in cancer therapySemantic proximity Read ↗

Copper Complexes as Anticancer AgentsSemantic proximity Read ↗

Progress of Metal‐Based Anticancer Chemotherapeutic Agents in Last two Decades and their Comprehensive Biological (DNA/RNA Binding, Cleavage and Cytotoxicity Activity) StudiesSemantic proximity Read ↗

Platinum Complexes as Anticancer AgentsSemantic proximity Read ↗

Synthesis and characterization of Cu(II)-based anticancer chemotherapeutic agent targeting topoisomerase Iα: In vitro DNA binding, pBR322 cleavage, molecular docking studies and cytotoxicity against human cancer cell linesSemantic proximity Read ↗

Copper(II) Phenanthroline-Based Complexes as Potential AntiCancer Drugs: A Walkthrough on the Mechanisms of ActionSemantic proximity Read ↗

Zinc(ii) complexes containing bis-benzimidazole derivatives as a new class of apoptosis inducers that trigger DNA damage-mediated p53 phosphorylation in cancer cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.