Article

Mutations in ErbB2 accumulating in the male germline measured by error-corrected sequencing

2024-09-06

Abstract excerpt

<title>Abstract</title> <p>Mutations in the male germline are a driving force behind rare genetic diseases. Driver mutations enjoying a selective advantage expand to mutant clusters within the aged testis, and are thus overrepresented in sperm with age. Other kinds of driver mutations, occurring pre-pubescently, are the focus of recent attention given their high occurrence independent of age. Here, we investigate...

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Literature Corpus work: 34a5407a-bf10-5a40-9c38-643e692c7afe
DOI: 10.21203/rs.3.rs-4887284/v1

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