Article

Mutations in ErbB2 accumulating in the male germline measured by error-corrected sequencing

2024-08-16

Abstract excerpt

Mutations in the male germline are a driving force behind rare genetic diseases. Driver mutations enjoying a selective advantage expand to mutant clusters within the aged testis and are thus overrepresented in sperm with age. Other kinds of driver mutations, occurring prepubescently, have been the focus of recent attention given their high occurrence rate independent of age. Here, we investigated the ErbB2 gene vi...

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Literature Corpus work: f7250392-06ee-5d82-bfaa-f503bacf89d9
DOI: 10.1101/2024.08.14.607923

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