Article

Differential variant calling in mutants from diverse genetic backgrounds: A case study in the nematode <i>Pristionchus pacificus</i>

2017-05-16

Abstract excerpt

Genome sequencing of mutants is one of the most widely used techniques to identify genes that control traits of interest including human diseases. Traditionally, variants are called against reference genomes and various filtering techniques are applied to reduce the number of candidate mutations. However, if the genetic background of the mutant is different from the reference genome, the number of background varia...

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Literature Corpus work: 3462adf0-e02a-5fa1-bb23-0ff09e3b388f
DOI: 10.1101/138479

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