Article

Snail-Regulated Exosomal MicroRNA-21 Suppresses NLRP3 Inflammasome Activity to Enhance Chemoresistance

2021-09-29

Abstract excerpt

<title>Abstract</title> <p>Compared to the precise targeting of drug-resistant mutant cancer cells, strategies for eliminating non-genetic adaptation-mediated resistance are limited. The pros and cons of the existence of inflammasomes in cancer have been reported. Nevertheless, the dynamic response of inflammasomes to therapies should be addressed. Here, we have demonstrated that in cancer cells undergoing Snail-...

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Literature Corpus work: 342ec988-0893-5513-9bc3-dd27d7c19f79
DOI: 10.21203/rs.3.rs-877605/v1

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