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Article

Image-based quantification of histological features as a function of spatial location using the Tissue Positioning System

2022-10-17

Abstract excerpt

<h4>ABSTRACT</h4> Tissues such as the liver lobule, kidney nephron, and intestinal gland exhibit intricate patterns of zonated gene expression corresponding to distinct cell types and functions. To quantitatively understand zonation, it would be important to measure cellular or genetic features as a function of position along a zonal axis. While it is possible to manually count, characterize, and locate features...

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Literature Corpus work
33e67887-cf94-579e-b324-b19b92bf96bf
DOI
10.1101/2022.10.12.511979
Open publication

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Image-based quantification of histological features as a function of spatial location using the Tissue Positioning SystemDOI 10.1101/2022.10.12.511979
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