Article

Gemcitabine as chemotherapy of head and neck cancer in Fanconi anemia patients

2023-08-24

Abstract excerpt

<title>Abstract</title> <p>Fanconi anemia (FA) is a rare hereditary disease characterized by an inactivating mutation in the FA/BRCA pathway, critical for the effective repair of DNA interstrand crosslinks (ICLs). The disease is characterized by progressing bone marrow failure, congenital abnormalities and an increased risk to develop malignancies early in life, in particular head and neck squamous cell carcinoma...

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Literature Corpus work: 3346bc72-d927-57ba-b230-d6918d7a5ce3
DOI: 10.21203/rs.3.rs-3251364/v1

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