Article

TBC1D23 drives lymphatic metastasis in pancreatic ductal adenocarcinoma by altering EGFR cell surface dynamics and signaling

2022-07-06

Abstract excerpt

<title>Abstract</title> <p>Rich in protein and adjacent to pancreatic cancer cells, pancreatic juice has been considered an attractive source to discover biomarkers for pancreatic ductal adenocarcinoma (PDAC). Here, we identified a novel biomarker, TBC1D23 in pancreatic juice of PDAC patients. High TBC1D23 expression was also observed in tumor tissues and sera, associated with lymphatic metastasis and shorter sur...

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Literature Corpus work: 33464f50-cc5f-559f-9d64-7d69a2ec988b
DOI: 10.21203/rs.3.rs-1774960/v1

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