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Is glucose-6-phosphate dehydrogenase deficiency associated with COVID-19 infection, severity, and death? A cohort study from the Brazilian Amazon

2025-08-26

Abstract excerpt

<h4>Background</h4> Glucose-6-phosphate dehydrogenase deficiency (G6PDd) is a common genetic disorder that impairs the cellular antioxidant response and has been hypothesized as a potential risk factor for severe outcomes in viral infections, including COVID-19. However, clinical evidence remains limited, especially in regions with high G6PDd prevalence. <h4>Methods</h4> We conducted a retrospective cohort study...

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Literature Corpus work
704b8f0a-85a2-52ef-82fc-f737dd23c37f
DOI
10.1101/2025.08.21.25334198
Open publication

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Is glucose-6-phosphate dehydrogenase deficiency associated with COVID-19 infection, severity, and death? A cohort study from the Brazilian AmazonDOI 10.1101/2025.08.21.25334198
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