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A non-Dicer RNase III and four other novel factors required for RNAi-mediated transposon suppression in the human pathogenic yeast <i>C. neoformans</i>

2019-03-14

Abstract excerpt

The human pathogenic yeast Cryptococcus neoformans silences transposable elements using endo-siRNAs and an Argonaute, Ago1. Endo-siRNAs production requires the RNA-dependent RNA polymerase, Rdp1, and two partially redundant Dicer enzymes, Dcr1 and Dcr2, but is independent of histone H3 lysine 9 methylation. We describe here an insertional mutagenesis screen for factors required to suppress the mobilization of the...

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Literature Corpus work
32afc16c-cd83-5d63-b54b-203055beaf2a
DOI
10.1101/577924
Open publication

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A non-Dicer RNase III and four other novel factors required for RNAi-mediated transposon suppression in the human pathogenic yeast <i>C. neoformans</i>DOI 10.1101/577924
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