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Article

RNA Interference in the Pathogenic Fungus <i>Cryptococcus neoformans</i>

1 Feb 2002

Abstract excerpt

Cryptococcus neoformans is a pathogenic fungus responsible for serious disease in immunocompromised individuals. This organism has recently been developed as an experimental system, with initiation of a genome project among other molecular advances. However, investigations of Cryptococcus are hampered by the technical difficulty of specific gene replacements. RNA interference, a process in which the presence of...

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PMID: 11861553
DOI: 10.1093/genetics/160.2.463

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