Article

Global Evaluation of Congenital Heart Disease-Associated Non-Coding Variants

2025-12-05

Abstract excerpt

<h4>Abstract (Summary)</h4> Genome-wide association studies (GWAS) have mapped thousands of congenital heart disease (CHD)-associated variants within non-coding regions of the genome. Non-coding variants can alter regulatory mechanisms, such as transcription factor (TF) binding control of gene expression, potentially contributing human diseases. However, with the increasing number of disease-associated variants,...

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Literature Corpus work: 31fafe70-d1b1-5bb0-8321-042259d1fcea
DOI: 10.64898/2025.12.02.691900

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