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Multiomics analysis reveals the involvement of NET1 in tumour immune regulation and malignant progression

2 Jan 2025

Abstract excerpt

Neuroepithelial cell transforming gene 1 (NET1) is a member of the Ras homologue family member A (RhoA) subfamily of guanine nucleotide exchange factors and a key protein involved in the activation of Rho guanosine triphosphatases, which act as regulators of cell proliferation, cytoskeletal organization, and cell movement and are crucial for cancer spread. Research has shown that NET1 can regulate the malignant...

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PMID: 39747410
DOI: 10.1038/s41598-024-83714-8

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