Article

Microglia do not restrict SARS-CoV-2 replication following infection of the central nervous system of K18-hACE2 transgenic mice

2021-11-17

Abstract excerpt

Unlike SARS-CoV-1 and MERS-CoV, infection with SARS-CoV-2, the viral pathogen responsible for COVID-19, is often associated with neurologic symptoms that range from mild to severe, yet increasing evidence argues the virus does not exhibit extensive neuroinvasive properties. We demonstrate SARS-CoV-2 can infect and replicate in human iPSC-derived neurons and that infection shows limited anti-viral and inflammatory...

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Literature Corpus work: 31d12ba9-ccdc-5a8a-b502-806be3909993
DOI: 10.1101/2021.11.15.468761

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Microglia do not restrict SARS-CoV-2 replication following infection of the central nervous system of K18-hACE2 transgenic miceDOI 10.1101/2021.11.15.468761Read

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