Article

Specific activation of HIV-1 from monocytic reservoir cells by bromodomain inhibitor in humanized mice in vivo

2018-07-24

Abstract excerpt

<h4>ABSTRACT</h4> The combination antiretroviral therapy (cART) effectively suppresses HIV-1 infection and enables HIV-infected individuals to live long productive lives. However, the persistence of HIV-1 reservoir cells with latent or low-replicating HIV-1 in patients under cART make HIV-1 infection an incurable disease. Recent studies have focused on the development of strategies such as epigenetic modulators t...

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Literature Corpus work: 31427986-f260-5467-b848-8526d54304bf
DOI: 10.1101/375535

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