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Lost in Transcription: Molecular Mechanisms that Control HIV Latency

21 Mar 2013

Abstract excerpt

Highly active antiretroviral therapy (HAART) has limited the replication and spread of the human immunodeficiency virus (HIV). However, despite treatment, HIV infection persists in latently infected reservoirs, and once therapy is interrupted, viral replication rebounds quickly. Extensive efforts are being directed at eliminating these cell reservoirs. This feat can be achieved by reactivating latent HIV while...

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PMID: 23518577
DOI: 10.3390/v5030902

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