Article

A Single-Short Partial Reprogramming of the Endothelial Cells decreases Blood Pressure via attenuation of EndMT in Hypertensive Mice

2024-05-21

Abstract excerpt

<h4>Background</h4> Small artery remodeling and endothelial dysfunction are hallmarks of hypertension. Growing evidence supports a likely causal association between cardiovascular diseases and the presence of endothelial-to-mesenchymal transition (EndMT), a cellular transdifferentiation process in which endothelial cells (ECs) partially lose their identity and acquire additional mesenchymal phenotypes. EC reprogr...

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Literature Corpus work: 311e743f-c245-5742-85d5-add45ad23cd7
DOI: 10.1101/2024.05.20.595057

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