Article

Hidden Interactions: Frequency-Dependence Emulates Selection-Driven Dynamics in Evolving Populations

2023-03-16

Abstract excerpt

The temporal evolution of mutating pathogens in disease contexts arises from both the intrinsic properties of each subpopulation and the interactions among them, yet experimental inference often neglects the latter. Drug development studies commonly estimate selective advantages by comparing growth rates in monoculture, and in vitro monoculture dose-response curves are frequently used to justify or halt further in...

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Literature Corpus work: 309fc755-78eb-570d-ad80-4987adde9ece
DOI: 10.1101/2023.03.15.532871

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