Article

Amygdalar CB2 cannabinoid receptor mediates fear extinction deficits promoted by orexin-A/hypocretin-1

2021-12-09

Abstract excerpt

<h4>Background: </h4> and purpose: Anxiety is often characterized by an inability to extinguish learned fear responses. Orexins/hypocretins are involved in the modulation of aversive memories, and dysregulation of this system may contribute to the aetiology of anxiety disorders characterized by pathological fear. The mechanisms by which orexins regulate fear remain unknown. Experimental approach: We investigated t...

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Literature Corpus work: 307a6834-201e-59ab-bcef-100e6828998c
DOI: 10.22541/au.163908388.84110482/v1

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