Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Learned phenotypes emerge during social stress modifying hippocampal orexin receptor gene expression.

Scientific reports - 30 Dec 2024

Yaeger Jazmine D W, Achua Justin K, Booth Clarissa D, Khalid Delan, John Megan M, Ledesma Leighton J, Greschke Trent L, Potter Ashley M, Howe Chase B, Krupp Kevin T, Smith Justin P, Ronan Patrick J, Summers Cliff H

Abstract excerpt

Psychological distress, including anxiety or mood disorders, emanates from the onset of chronic/unpredictable stressful events. Symptoms in the form of maladaptive behaviors are learned and difficult to treat. While the origin of stress-induced disorders seems to be where learning and stress intersect, this relationship and molecular pathways involved remain largely unresolved. The hippocampus, studied for its...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Expression Regulation
Share to Hippocampus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Learning

Share to Mice, Inbred C57BL

Share to Orexin Receptors

Share to Phenotype

Share to Stress, Psychological

Source

Open in PubMed Open full text

Identifiers

PMID: 39738291
DOI: 10.1038/s41598-024-81590-w
PMCID: PMC11685668

Genes

CA2
CA1
CA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Learned phenotypes emerge during social stress modifying hippocampal orexin receptor gene expression.PMID 39738291Read ↗

Reactivation of early-life stress-sensitive neuronal ensembles contributes to lifelong stress hypersensitivitySemantic proximity Read ↗

Effects of early life adversity on immediate early gene expression: systematic review and 3-level meta-analysis of rodent studiesSemantic proximity Read ↗

Subcortical-hippocampal circuits for mediating impaired contextual fear memory after an acute shift of the light/dark phaseSemantic proximity Read ↗

Transcriptomic profiles of susceptibility and resilience to stress in the amygdala and hippocampus of male ratsSemantic proximity Read ↗

Transcriptional profiles underlying vulnerability and resilience in rats exposed to an acute unavoidable stress.Semantic proximity Read ↗

mRNA and microRNA Profiles in the Amygdala Are Relevant to Susceptibility and Resilience to Psychological Stress Induced in Mice.Semantic proximity Read ↗

Spatiotemporal remodeling in the habenula marks the onset of depressionSemantic proximity Read ↗

Deep phenotyping reveals CRH and FKBP51-dependent behavioral profiles following chronic social stress exposure in male mice.Semantic proximity Read ↗

Easy to remember, difficult to forget: the development of fear regulation.Semantic proximity Read ↗

Characterization of transcriptional profiles associated with stress-induced neuronal activation in Arc-GFP miceSemantic proximity Read ↗

Stress susceptibility-specific phenotype associated with different hippocampal transcriptomic responses to chronic tricyclic antidepressant treatment in mice.Semantic proximity Read ↗

Predicting extinction phenotype to optimize fear reduction.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.