Article

Machine learning-guided design of artificial microRNAs for targeted gene silencing

2026-02-14

Abstract excerpt

Artificial microRNAs (amiRNAs) offer a powerful strategy for targeted gene silencing, but their rational design is limited by complex sequence-structure-processing relationships and the lack of tools capable of optimizing efficacy and specificity. To address this need, we developed miRarchitect, a web-based platform that uses machine learning to support the customizable design of amiRNAs. miRarchitect integrates n...

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Literature Corpus work: 3050ca68-f3ec-5fbd-a3b7-b0d23ceb7336
DOI: 10.64898/2026.02.12.705546

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